In this unique course we teach quantitative methods and biological concepts together, through application of the methods to cutting-edge biological research problems. The focus is on current topics in modern quantitative biology, such as interactions between ecological and evolutionary dynamics, and the effects of climate change on ecological communities. You will also have the chance to develop your knowledge in mathematical, statistical, and computing tools through their application to important research problems. Over the past 10–20 years, biology has become increasingly quantitative, and mathematical sciences have in turn been increasingly influenced by biology. It has been said that “mathematics is biology's next microscope, only better” (Cohen, Plos Biology, 2004) because mathematical, statistical, and computational sciences will continue to reveal unsuspected and entirely new worlds within biology, just as the microscope revealed previously unseen worlds following its invention. It has also been said that “biology is mathematics' next physics, only better” (Cohen, Plos Biology) because biology will in turn continue to spur major new developments in computation, mathematics and statistics, just as physics has done in past centuries.